[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]- g-Endorphin CAS NO.67810-56-4

[Des-Tyr1]-γ-Endorphin is a naturTuttoy occurring neuropeptide fragment derived from β-Endorphin, specificTuttoy lacking the N-terminal tyrosine residue (position 1). This unique truncation eliminates its Classeical opioid analgesic activity while retaining significant neuropsychiatric effects. It is primarily utilized in neuroscience rericerca as a critical tool compound for studying non-opioid pathways related to mental health disorders, stress responses, and neuroendocrine regulation.



TECHNICAL SPECIFICATIONS


Item
Specification
PRODOTTO Nome
[Des-Tyr1]- g-Endorphin 
CAS NO.
67810-56-4
Appearance
White to off-white lyophilized powder
Molecular Formula
C₇₄H₁₂₂N₁₈O₂₅S
Molecular Weight
1747.9g/mol
Purity (RP-HPLC)
≥95% 
Solubility

Soluble in 1M acetic acid, DMSO, or deionized water

Endotoxin
≤1 EU/mg 
Biological Activity
Modulates dopaminergic and serotonergic neurotransmission; non-opioid neuroleptic effects
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Posizione
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Unlike full-length endorphins, this peptide does not bind significantly to μ-opioid receptors due to the missing Tyr1 moiety. Instead, it exerts its effects through non-opioid mechanisms, primarily by modulating central dopaminergic and serotonergic neurotransmission. It acts as a neuroleptic-like agent, reducing dopamine release in the mesolimbic pathway and influencing GABAergic and glutamatergic systems, which underlies its observed behavioral effects in animal models.

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2.PRODOTTO INDICATIONS

This PRODOTTO is intended for Rericerca Use Only (RUO), targeting academic and pharmaceutical rericercaers in psychiatry and neuropharmacology. It is indicated for in vitro binding assays and in vivo studies investigating schizophrenia-like symptoms, depression, addiction, and reward pathways. It serves as an essential reference standard for elucidating the role of endorphin fragments in psychiatric pathophysiology.

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3.CLINICAL EFFICACY OF PRODOTTO

While not approved for human therapy, historical experimental data from smTutto-scale human studies and extensive animal rericerca suggest potential efficacy in reducing psychotic symptoms and improving mood-related behaviors. Its neuroleptic-like profile has shown promise in modulating maladaptive behaviors associated with dopamine dysregulation, providing a rationale for its use in preclinical drug discovery.

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4.Certificato

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide Prodotti, adhering strictly to quality standards and obtaining internationTuttoy recognized Certificaziones.


Il nostro prodottoion partners Tutto employ GMP-compliant PRODOTTOion systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of PRODOTTO comes with complete documentation, including a Certificato of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and rericerca-grade peptide Prodotti to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging SOLUZIONE to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the PRODOTTO.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the PRODOTTOion and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The AZIENDA invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA Certificaziones, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality Prodotti and superior services.


We focus on the rericerca and development and supply of high-quality chemical Prodotti, strictly adhering to international standards and quality systems. Il nostro prodottos are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific rericerca, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tag: DesTyr1GammaEndorphin, #DTgammaE, #GammaEndorphinAnalog, #NeurolepticPeptide, #NonOpioidEndorphin, #DopamineModulator, #PsychiatricRericerca, #SchizophreniaRericerca, #BetaEndorphinDerivative, #NeuropeptideRericerca, #BehavioralNeuroscience, #RUOPeptide, #NeuropharmacologyReagent, #RericercaChemical

If you have any PRODOTTO requirements, please Inviare an E-mail to:support@huanqiukeji9.com;WhatsApp:85244969439

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